2024-2028
Anticipated
Doctor of Philosophy in Clinical Medicine
Neuronal Physiology and Pathology
Nuffield Department of Medicine, University of Oxford | Oxford, UK
Molecular Neuroscience & Synaptic Biology
Kaixin Zhang
张恺心
DPhil Student in Clinical Medicine, University of Oxford
My research focuses on the molecular and cellular mechanisms underlying neuronal health and disease, with particular interests in intracellular trafficking, synaptic biology and iPSC-derived models of neuronal disease.
About
Academic Background
2023-2024
Master of Science in Pharmacology
Neuropharmacology
Department of Pharmacology, University of Oxford | Oxford, UK
Distinction | Grade: 75%
2021-2023
Bachelor of Science (Hons)
Biomedical Sciences
School of Biological Sciences, University of Manchester | Manchester, UK
Second-One | Grade: 68%
2018-2022
Bachelor of Science
Biological Sciences
School of Life Sciences, Jilin University (吉林大学) | Changchun (长春), China
Grade: 90%
Research
Synapses, Organelles and Disease
Endophilin-A and Rabconnectin-3a/DMXL2 interaction in synaptic vesicle recycling, V-ATPase regulation, lysosomal function and neuronal disease.
Synaptic vesicle recyclingEndophilin-ADMXL2Rabconnectin-3aV-ATPaseLysosomesiPSC neurons
iPSC-derived cortical neuron models for disease-relevant cellular phenotyping.
High-content imaging and microscopy to quantify synaptic, vesicular and lysosomal biology.
Omics, molecular biology and targeted perturbation approaches to connect mechanism with neuronal phenotype.
Projects
Selected Work
Oxford Centre for Human Genetics
DPhil Project
Mechanistic study of Endophilin-A and Rabconnectin-3a/DMXL2 in synaptic vesicle recycling, V-ATPase regulation and neuronal disease.
Collaborative neuroscience
LANCL3 iPSC Collaboration
Collaborative iPSC-based work exploring neuronal phenotypes and molecular pathways linked to LANCL3 biology.
MSc Pharmacology, Oxford
MSc ATP6V0A1 Project
MSc research on ATP6V0A1-linked neuronal disease mechanisms, with emphasis on cellular pharmacology and organelle biology.
Visual science
Design and Scientific Communication
Scientific figures, posters, BioRender-style illustrations and web/design work for clear communication of complex biology.
Outputs
Publications and Posters
Publication
Manuscript in preparation
Synaptic vesicle biology and neuronal disease
Placeholder
Poster
DPhil research poster
Conference presentation
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Presentation
Research seminar or conference talk
University or society meeting
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Portfolio
Scientific Design Portfolio
01
Synaptic vesicle cycle figures
02
Rabconnectin-3a/DMXL2 pathway illustrations
03
iPSC-derived neuron schematics
04
Microscopy figure panels
05
Conference posters
06
Academic web and design work